Research Article
Modeling Periodic HFMD with the Effect of Vaccination in Mainland China
Table 1
Descriptions and values of parameters in system (
1).
| | Para. | Value | Interpretation (units) | Source |
| | | The monthly number of children entering the age of 6–71 months (/month) | [38] | | D | | Progression rate leaving the children group aged 6–71 months (/month) | [38] | | 0.56 | Proportion of infectious individuals, without vaccination, caused by HFMD-associated enteroviruses except EV71 (none) | [39] | | μ | | Disease-related death rate of HFMD (/month) | [8, 9] | | p | 0.23 | Vaccinated rate for children aged 6–71 months (/month) | Fitting | | | Rate from to (/month) | [24] | | | Rate from to (/month) | Assumption | | 4/30 | Average incubation period (/month) | [2] | | ρ | 0.23 | Proportion of symptomatic infectious individuals (none) | Fitting | | 3.53 | Recovery rate of symptomatic infectious individuals containing and (/month) | [2] | | 3.46 | Recovery rate of asymptomatic infectious individuals containing and (/month) | Fitting | | | The baseline contact rate of symptomatic infectious individuals containing and (none) | Fitting | | 0.12 | The magnitude of forcing of symptomatic infectious individuals containing and (none) | Fitting | | 0.22 | The magnitude of forcing of symptomatic infectious individuals containing and (none) | Fitting | | 0.03 | The magnitude of forcing of symptomatic infectious individuals containing and (none) | Fitting | | 0.15 | The magnitude of forcing of symptomatic infectious individuals containing and (none) | Fitting | | | The baseline contact rate of asymptomatic infectious individuals containing and (none) | Fitting | | 0.08 | The magnitude of forcing of asymptomatic infectious individuals containing and (none) | Fitting | | 0.19 | The magnitude of forcing of asymptomatic infectious individuals containing and (none) | Fitting | | 0.13 | The magnitude of forcing of asymptomatic infectious individuals containing and (none) | Fitting |
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