Modelling and Analysis of Virotherapy of Cancer Using an Efficient Hybrid Soft Computing Procedure

Figure 3

Problem 1: graphical evaluation tumor growth ratio (r) to rate of cell lysis () , the inverse of burst size parameter , and the viral decay () ratio to rate of cell lysis () . (a) Solution for f = 0,  = 0.02, and h = 0.15 with initial conditions I (0) = 0.6, U (0) = 0, and V (0) = 0.5, (b) weights obtained by ANN-SCA-SQP for CVRT, (c) solutions of 100 independent runs of uninfected cells, I (t), (d) solutions of 100 independent runs of infected cells, U (t), and (e) solutions of 100 independent runs of free viruses, V (t).

(a)

(b)

(c)

(d)

(e)