Table of Contents
Conference Papers in Medicine
Volume 2013 (2013), Article ID 583175, 5 pages
http://dx.doi.org/10.1155/2013/583175
Conference Paper

Small Changes in Cardiac Troponin Levels Are Common in Patients with Myocardial Infarction: Diagnostic Implications

Department of Clinical Chemistry and Transfusion Medicine, Bruna stråket 16, Sahlgrenska Academy at The University of Gothenburg, 413 45 Gothenburg, Sweden

Received 15 January 2013; Accepted 1 April 2013

Academic Editors: A. Bellou, E. Giannitsis, C. Hamm, M. Möckel, and J. Searle

This Conference Paper is based on a presentation given by O. Hammarsten at “Clinical Decisions in Acute Patients: ACS–POCT–Hypertension and Biomarkers” held from 19 October 2012 to 20 October 2012 in Berlin, Germany.

Copyright © 2013 O. Hammarsten. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Changes in cardiac troponin (cTn) levels are often evaluated when myocardial infarction (MI) is suspected. The change in the troponin level required for diagnosis is being debated but should exceed the natural biological variation according to current guidelines. Despite this, several reports show that MI patients often present at the emergency ward with relatively stable cTn elevations. In this review we discuss the potential problem using a small cTn change as a way to exclude MI and also provide a possible solution to this diagnostic problem using long-term cTn change.