Case Report

A Minimal-Invasive Metabolic Test Detects Malignant Hyperthermia Susceptibility in a Patient after Sevoflurane-Induced Metabolic Crisis

Table 2

In vitro contracture test results. A contracture 2 mN at the defined threshold concentrations of caffeine 2 mM and halothane 0.44 mM confirmed MH susceptibility.

CaffeinePredrug0,5 mM1 mM1,5 mM2 mM3 mM4 mM32 mM

Test 114.0 mN13.5 mN15.6 mN19.6 mN25.6 mN29.1 mN29.1 mN144 mN
Test 212.7 mN12.2 mN13.0 mN17.8 mN24.7 mN35.7 mN32.2 mN209 mN

HalothanePredrug0,11 mM0,22 mM0,44 mM0,66 mM

Test 111.6 mN23.0 mN35.1 mN32.1 mN26.5 mN
Test 219.1 mN20.9 mN28.1 mN29.5 mN26.8 mN