Successful Ultrasound-Guided Femoral Nerve Blockade and Catheterization in a Patient with Von Willebrand Disease

Table 1

Available literature on outcomes of femoral nerve blockade in patients on thromboprophylaxis and/or at above-standard bleeding risk.

Author	Study type	Nb. of blocks	Type of block	ppx or bleeding risk	Complication(s) from femoral block
Chelly and Schilling [6]	Retrospective cohort	1790	Continuous femoral	10% aspirin ppx; 20% LMWH ppx; 10% fondaparinux ppx; 60% warfarin ppx	0
Vanarase et al. [7]	Retrospective cohort	21	Single-shot femoral or sciatic or both	2 vWD patients; 13 hemophilia patients	0
Sripada et al. [8]	Case report	2	Single-shot femoral and sciatic	2 hemophilia patients	0
Wiegel et al. [9]	Retrospective cohort	628	Continuous femoral	Not specified	36 vascular punctures; 1 retroperitoneal hematoma causing permanent nerve injury
Bickler et al. [10]	Case report	2	Continuous femoral and sciatic	LMWH ppx	1 swelling & discoloration at block site with temporary lower extremity motor impairment; 1 delayed oozing at catheter site
Rodríguez et al. [11]	Case report	1	Single-shot femoral and sciatic	Factor XI deficiency, LMWH ppx	Perineural hematoma with temporary lower extremity paralysis

Nerve injury was evidenced by complete quadriceps femoris denervation. The concerned patient was reportedly self-administering 1 g of aspirin daily pre- and postoperatively, unbeknownst to her caregivers.
Nb. indicates number; ppx, thromboprophylaxis; LMWH, low molecular weight heparin.