Erroneous Activated Coagulation Time During Atrial Flutter Ablation

Table 2

Tests available to confirm presence of heparin in blood.

Test	Platform	Location	Time to result	Ease of performance
ACT	Multiple	POC	<10 mins	Simple
Protamine titration	Hepcon HMS	POC	<10 mins	Simple
	Hemochron Rx/Dx
r-time and Heparinase r-time	TEG	POC or central lab	<15 mins	Moderate
INTEM and HEPTEM	ROTEM	POC or central lab	<15 mins	Moderate
CT and HCT	Quantra	POC	<15 mins	Simple
APTT	Multiple	Central lab	45–90 mins	Complex
Anti-Xa	Multiple	Central lab	45–90 mins	Complex

ACT = activated coagulation time; POC = point-of-care; HMS = heparin management system; TEG = thromboelastography; INTEM = screening test of hemostasis performed on ROTEM; HEPTEM = INTEM performed in presence of heparinase; ROTEM = rotational thromboelastometry; CT = clotting time; HCT = heparinase clotting time; APTT = activated partial thromboplastin time; Anti-Xa = anti-Xa assay. Note: Time to anti-Xa result assumes a lab that reconstitutes reagents and runs controls daily.