Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy

Table 1

Pulmonary function tests.

	Prepregnancy	13 weeks	22 weeks	30 weeks	9 months postpregnancy
TLC	56%	54%	53%	56%	59%
FVC	49%	47%	41%	48%	49%
FEV1	49%	51%	45%	53%	52%
FEV1/FVC	99%	108%	109%	110%	104%
DLCO	34%	40%	31%	37%	35%
O2 requirements with activity and at night	None	3L NC	3L NC	3L NC	None

Values are represented as fractions of predicted normal values. Normal values are the following (95% confidence interval): TLC, total lung capacity (80%–120%); FVC, forced vital capacity (80%–120%); FEV1, forced expiratory volume at one second (80%–120%); FEV1/FVC, percentage of the FVC expired in one second (within 5% of the predicted ratio); DLCO, diffusing capacity of the lung for carbon monoxide (>60% to <120%).