Case Report

Successful Anesthetic Management of an Adult with Sotos Syndrome

Table 1

Summary of previously documented Sotos syndrome anesthetic management.

YearAuthorAgeWeight (kg)SexSurgeryPremedicationInductionAnestheticParalyticAnalgesiaAirwayIntraoperative complications

2021Winegarner et al.1841MDental extractions and restorationMidazolam 15 mg (gastric tube)Mask, 50% N2O, 8% sevo, propofol 1.2 mg/kgSevofluraneRocuronium 0.7 mg/kgHydromorphone 12 mcg/kgETT 1st attempt, grade 1 viewDelayed emergence attenuated with naloxone
2017Chung et al.419.4MHydrocelectomyGlycopyrrolate 100 mcg IMThiopental 5 mg/kgSevofluraneRocuronium 0.3 mg/kgFentanyl 1 mcg/kgETT 1st attempt, grade 1 viewNone
2011Chierichini et al.7NAMFlat foot surgeryNoneSevofluraneRegionalNoneSciatic nerve block with 10 ml of ropivacaine 0.5%NANone
2003Adhami et al.2.517MInguinal hernia repairAtropine 11.8 mcg/kgMask, 50% N2O, 8% sevoN2O and sevofluraneNoneNAETT 1st attempt, grade 1 viewNone
2003Adhami et al.1.514.8MInguinal hernia repairNANANACisatracurium 0.2 mg/kgMorphine 68 mcg/kgETT 1st attempt, grade 1 viewNone
2001Varvinski et al.1355FTibia repairNAThiopental 5.45 mg/kgSevofluraneSuccinylcholine 1.81 mg/kgFentanyl 1.36 mcg/kgETT 1st attempt, grade 1 viewNone
1993de Nadal et al.1380MParietal bone resectionAtropine 10 mcg/kgThiopental 5 mg/kgN2O and IsofluraneAtracurium 0.5 mg/kgFentanyl 2 mcg/kgNasal intubation failed, 2nd attempt with oral ETTNone
1993de Nadal et al.110.6MBrain tumor resectionAtropine 10 mcg/kgThiopental 5 mg/kgN2O and isofluraneNAFentanyl 1 mcg/kgNasal intubationNone
1991Suresh1490MSpinal fusionDiazepam 10 mg, oralHalothaneN2O and halothaneVecuronium 0.1 mg/kgMeperidineETTNone
1991Suresh14NAMSpinal fusion revisionNAThiopentalN2O and enfluraneSuccinylcholine and vecuroniumPapaveretumNANone
1991Jones et al.NA15.6–25.8NAHernia repairs, Harrington rodsTrimeprazineHalothane, enflurane, or thiopentaneIsofluraneAtracurium and alcuroniumMorphine and fentanylETT without incident on each occasionNone

ATT, attempt; ETT, endotracheal tube; NA, not specified in the article; NI, nasal intubation; UGSNB, ultrasound-guided sciatic nerve block. Doses are specified in the table if they were provided in their respective reports. The Adhami et al. 2003 report described two anesthetics given to the same patient at 18 months and 30 months old. The Suresh et al. 1991 report describes two anesthetics given to the same patient separated by a week. The Jones et al. 1991 report described five anesthetics given to one patient over a period of three years.