Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Cardiology
Volume 2012, Article ID 646505, 3 pages
Case Report

Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia

1Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands
2Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands

Received 20 June 2012; Accepted 16 August 2012

Academic Editors: C. D. Barrett, C. Firschke, A. J. Mansur, and K. Roberts-Thomson

Copyright © 2012 Sebastiaan Velthuis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting millions of individuals worldwide, and a major risk factor for disabling cerebral embolic stroke. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disorder, characterized by vascular abnormalities with high-bleeding tendency and therefore intolerance for oral anticoagulation. We report a case of percutaneous closure of the left atrial appendage, which might be a good alternative strategy instead of chronic oral anticoagulation to protect patients with high-risk AF and HHT from cerebral embolic strokes.