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Case Reports in Cardiology
Volume 2016 (2016), Article ID 2359532, 4 pages
Case Report

Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis

1Departamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, Mexico
2Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Estado de México, Mexico

Received 30 November 2015; Accepted 6 January 2016

Academic Editor: Ertuğurul Ercan

Copyright © 2016 Mario Enrique Baltazares-Lipp et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hypereosinophilic syndrome (HES) is a rare disorder with unknown global prevalence, barely reported in Hispanic population, and characterized by persistent eosinophilia in association with organ dysfunctions directly attributable to eosinophilic infiltration. Cardiac involvement may be present in 50 to 60% of the patients. This is known as Löffler endocarditis. We present a case of a 36-year-old Hispanic man with signs of heart failure. Laboratory studies showed eosinophilia (23,100/μL). Thoracic computer tomography showed bilateral pleural effusion and a large left ventricular mass. Transthoracic echocardiography showed left ventricle apical obliteration and a restrictive pattern. Pulmonary angiography demonstrated a thrombus in the lingular and middle lobe. Despite treatment, the patient deceased seven days after admission. Autopsy confirmed the diagnosis of Löffler endocarditis.