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Case Reports in Cardiology
Volume 2016, Article ID 6809263, 4 pages
Case Report

Fibrinolytic Treatment after Transient Ischaemic Attack Caused by Prosthetic Mitral Valve Thrombosis

Immanuel Hospital Bernau Brandenburg Heart Center, Medical School Brandenburg, Ladeburger Straße 17, 16321 Bernau, Germany

Received 10 March 2016; Accepted 5 May 2016

Academic Editor: Filippo M. Sarullo

Copyright © 2016 Cornel Koban et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Prosthetic valve thrombosis is one of the most severe complications after surgical valve replacement. There are many possible presentations: from asymptomatic to life-threatening complications. We report on a 61-year-old female patient with prosthetic replacement of the aortic and mitral valve in the in-house department of cardiac surgery 3 months ago. The patient was suffering from aphasia during 5 minutes in domesticity. After her presentation in the emergency room, the echocardiographic examination revealed a thrombotic formation of the prosthetic mitral valve. At presentation, the anticoagulation was outside the effective range (INR: 1.7). A successful thrombolytic therapy with the plasminogen activator urokinase was begun with complete resolution of the thrombus.