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Case Reports in Cardiology
Volume 2016, Article ID 9219018, 4 pages
Case Report

Takotsubo Syndrome: A Pathway through the Pituitary Disease

1Hospital Santa Maria, Cardiology Department, Lisbon Academic Medical Centre, CCUL, Lisbon, Portugal
2Hospital de Santa Maria, Avenida Professor Egas Moniz, 1649-035 Lisboa, Portugal

Received 24 November 2015; Accepted 2 February 2016

Academic Editor: Man-Hong Jim

Copyright © 2016 Rui Plácido et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Takotsubo cardiomyopathy (TTC) is characterized by reversible left ventricular apical and/or midventricular hypokinesia with unknown etiology. The clinical presentation is similar to acute myocardial infarction in the absence of significant obstructive coronary artery disease. Various predisposing factors have been related to TTC, such as acute neurological illnesses, endocrine diseases, pain, and emotional stress. We present the first description of an association between TTC cardiomyopathy and panhypopituitarism. This case reinforces the connection between the hormonal and cardiovascular systems. Furthermore, it supports the importance of a comprehensive and integrated medical history in the approach of a patient with cardiac disease, towards clinical decision-making.