A Rare Presentation of Cardiac Tamponade from Metastatic Urothelial Carcinoma of the Bladder

Figure 3

(a) H&E section shows thickening and fibrosis of the pericardium (asterisk) and scattered aggregates of metastatic urothelial carcinoma (black arrows). Insert: high power view of the malignant cells. The pericardial effusion demonstrates 3D clusters of large highly atypical malignant cells (b, Papanicolaou stain), variable in size and hyperchromatic with a high nuclear to cytoplasmic ratio (c, Diff-Quick stain). The malignant cells are immunoreactive for uroplakin and MOC-31 while negative for calretinin (not shown).

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