Spontaneous Regression of Cardiac Rhabdomyoma Presenting as Severe Left Ventricular Inlet Obstruction in a Neonate with Tuberous Sclerosis

Figure 1

Two-dimensional echocardiography shows a large rhabdomyoma (arrowhead), 20.5 × 15.6 mm in diameter, occupying 75–90% of the mitral annulus, in addition to multiple small tubers in both ventricles and the left ventricular outflow tract after birth in apical 4-chamber (a), parasternal long-axis (b), and parasternal short-axis (c) views. Right atrial, right ventricular (RV), and left atrial dilatation were also observed. Pulse Doppler echocardiography showed a peak velocity through the mitral valve of 1.66 m/s (d). RV dilatation and pressure overload secondary to pulmonary hypertension were observed in a parasternal, end-diastolic short-axis view (e). The peak velocity through the tricuspid valve was 4.13 m/s (f).