| | Device | Manufacturer | Design | Sizes (mm) | Sheath (F) | Approval status |
| | Endocardial LAAO devices | | WATCHMAN | Boston Scientific | Single (lobe) | 21, 24, 27, 30, 33 | 14 | CE Mark (2005)
FDA (2015) | | WATCHMAN FLX | 20, 24, 27, 31, 35 | 14 | CE Mark (2019)
FDA (2020) | | Amplatzer Cardiac Plug | Abbot Vascular, formerly St. Jude Medical | Double (lobe and disc) | 16, 18, 20, 22, 24, 26, 28, 30 | 9-13 | CE Mark (2008) | | Amplatzer Amulet | 16, 18, 20, 22, 25, 28, 31, 34 | 12-14 | CE Mark (2013) | | WaveCrest | Biosense Webster, Inc. (Johnson and Johnson company) | Single (lobe) | 22, 27, 32 | 12 | CE Mark (2013) | | Occlutech | Occlutech International AB | Single (lobe) | 15, 18, 21, 24, 27, 30, 33, 36, 39 | 12, 14 | CE Mark (2016) | | LAmbre | Lifetech Scientific Co., Ltd. | Double (umbrella and cover) | 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36 | 8-10 | CE Mark (2016); CFDA (2017) | | Sideris transcatheter patch | Custom Medical Devices | Frameless, bioabsorbable, balloon-deliverable device | 15-25 | 13 | Undergoing clinical evaluation | | Ultraseal | Cardia, Inc. | Double (bulb and sail) | 16, 18, 20, 22, 24, 26, 28, 30, 32 | 10-12 | CE Mark (2016) | | SeaLA | Hangzhou Valued Medtech Co., Ltd. | Double (dual disc) | 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36 | 9-12 | Undergoing clinical evaluation | | LeFort | Lepu Medical Technology (Beijing) Co., Ltd. | Single (lobe) | 21-33 | — | Undergoing clinical evaluation | | Pfm device | Pfm Medical | Single (disc), dual anchor | — | 10-12 | Undergoing clinical evaluation |
| | Epicardial LAAO devices | | Lariat | SentreHeart, Inc. | Endoepidcardial | 40 (W), (45 [W] lariat +) x 20 (H) x 70 (L) | 12 | CE Mark (2015); FDA 510(k) (2006), surgical use only | | Sierra | Aegis Medical Innovations Inc. | Epicardial | Single size | 20 | Undergoing clinical evaluation |
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