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Case Reports in Critical Care
Volume 2011 (2011), Article ID 293917, 3 pages
http://dx.doi.org/10.1155/2011/293917
Case Report

Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion

Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain

Received 11 May 2011; Accepted 5 June 2011

Academic Editors: M. Egi and C. D. Roosens

Copyright © 2011 Yesica Rodríguez Santana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Severe hypertriglyceridemia (SH) represents a therapeutic emergency because of the possibility of developing cardiovascular events and hyperlipemic acute pancreatitis (PA). Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such as uncontrolled diabetes mellitus, alcoholism, and drug intake. The standard treatment of hypertriglyceridemia (HTG) with omega 3 fatty acids and fibrates, along with dietary changes, has no effect on an emergency situation. There are no clinical guidelines to SH, but therapy with insulin, heparin, a combination of both, plasmapheresis, or octreotide have been tested succesfully. We report the case of a 10-year-old girl with clinical acute pancreatitis and diabetic ketoacidosis debut, along with incidental finding of an SH, who had a good outcome after treatment with insulin intravenous infusion.