Case Report
Disseminated Histoplasmosis and Secondary Hemophagocytic Syndrome in a Non-HIV Patient
Table 1
Laboratory values on initial presentation and admission and during hospitalization.
| | Labs | Initial presentation | On admission
Day 1 | Days 3-4 | Day 8 |
| | Hemoglobin (g/dL) | 12.3 | 8.9 | 6.9 | 4.9 | | Hematocrit (%) | 38.2 | 26.6 | 22 | 13.7 | | WBC count (k/uL) | 5.6 | 4.9 | 7.9 | 10 | | Platelet (k/uL) | 283 | 144 | 92 | 48 | | Reticulocyte % | | 3.7 | 3.6 | | | D dimer assay (ng/mL) | | | 4162 | 26206 | | Fibrinogen (mg/dL) | | | 254 | 69 | | INR | 1.2 | 1.3 | 2.1 | 4.9 | | Activated partial thromboplastin time (seconds) | 31 | 31.3 | 34 | 59 | | LDH | 632 | 777 | 1466 | | | Haptoglobin | | 2 | 1 | | | (mL/min) | 87 | 121 | 87 | 20 | | Sodium (mEq/L) | 138 | 136 | 145 | 142 | | Potassium (mEq/L) | 4 | 4.4 | 4.2 | 4.4 | | Chloride (mEq/L) | 100 | 97 | 112 | 106 | | Bicarbonate (mEq/L) | 30 | 29 | 17 | 6 | | Calcium (mg/dL) | 10 | 8.6 | 8.2 | 7.7 | | Phosphorus (mg/dL) | | 4 | 4.2 | 8.5 | | Glucose (mg/dL) | 80 | 101 | 110 | 121 | | BUN (mg/dL) | 14 | 29 | 21 | 36 | | Creatinine (mg/dL) | 0.8 | 0.9 | 0.8 | 3 | | ALT (unit/L) | 70 | 184 | 3050 | 5058 | | AST (unit/L) | 59 | 214 | 6171 | 16637 | | Alkaline phosphatase (unit/L) | 95 | 139 | 329 | 763 | | Total protein (g/dL) | 7.7 | 5.5 | 6.4 | 3.4 | | Albumin (g/dL) | 4.8 | 3.4 | | 1.8 | | Total bilirubin (mg/dL) | 0.7 | 1.2 | 6.3 | 8.1 | | Direct bilirubin (mg/dL) | 0.3 | 0.6 | 5.1 | 3.1 | | Lactic acid (mmoles/L) | | 3 | 9.6 | 18 | | Ammonia (umole/L) | | | 126 | | | Ferritin (ng/mL) | | | 7493 | | | Triglycerides (mg/dL) | 133 | 145 | 135 | |
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