Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease

Table 1

Patient’s laboratory values during hospitalization until death.

Parameter
	Hour (hr) 0	hr 6	hr 15	hr 18	hr 22	hr 30
PT (seconds)	>169	275.3	57.7	61.1	72	130.3
INR	Unrecordable	23.8	5.1	5.4	6.4	11.4
PTT (seconds)	92	66.8	44.3	46.7	54.1	98.9
Serum albumin (g/dL)	2.8		2.4	2.6	2.1	1.8
Alanine aminotransferase (unit/L)	420		1234	1201	1312	2179
Aspartate transaminase (unit/L)	973		2475	2344	2548	3681
Alkaline phosphatase (unit/L)	435		393	369	403	379
Total bilirubin (mg/dL)	1		1.4	1.5	1.3	1.3
Lactic acid level (mmoles/L)	13.3		6.6	17	18	15
LDH (unit/L)			8003
Troponin (ng/mL)	0.21		0.32	0.48	0.88	1.58
CK (unit/L)	872		1059	1220	1179	1283
CK-MB (ng/mL)	40.42		44.01	53.75	66.06	72.28
CK-MB%	4.6		4.2	4.2	5.6	5.6
Haemoglobin (g/dL)	12		7.2	9.7	8.7	7.8
Bicarbonate (mEq/L)	10	13		5	6	3