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Case Reports in Critical Care
Volume 2018, Article ID 4243569, 3 pages
Case Report

Acute Chest Syndrome Progressing to ARDS in a Patient of 25-Week Gestation

1University of Illinois College of Medicine at Peoria, Peoria, IL, USA
2Illinois Lung Institute, Peoria, IL, USA

Correspondence should be addressed to Jefferson Chambers; moc.liamg@srebmahchnosreffej

Received 15 July 2017; Revised 1 January 2018; Accepted 3 January 2018; Published 30 January 2018

Academic Editor: Petros Kopterides

Copyright © 2018 Jefferson Chambers et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Acute chest syndrome is a complication of sickle cell disease and represents the highest cause of mortality in those afflicted with the disorder. Pregnancy represents an increased risk for complications of sickle cell disease in both the mother and fetus. We present a case of a 20-year-old patient with known sickle cell disease who was at 25-week gestation and developed acute chest syndrome refractory to conventional therapies and requiring emergency cesarean section. Following delivery, the patient developed acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO). The patient and infant eventually made full recoveries. This case highlights the importance of aggressive management of ACS and careful monitoring in a pregnant patient.