Case Report
Creutzfeldt-Jakob Disease Presenting as Expressive Aphasia and Nonconvulsive Status Epilepticus
| Variable | Value |
| Microbiology | | CSF | Negative for bacterial growth | Negative for acid fast bacilli (AFB) | Autoimmune panel serum: | | Microsomal TPO antibody | <0.2 IU/ml | Thyroxine binding globulin | 19.3 microgram/ml | Anti-TG Ab | <0.2 IU/ml | HIV 1/2 PCR | None | Lyme | 0.07 (Ref: ≤0.99 LIV) | FT Ab | Non-reactive | West Nile Virus (IgM) | None | SSA, 52 (Ro) | 1 AU/ml | SSA, 60 (Ro) | 1 AU/ml | Sjogren’s Ab | 0 AU/ml | ANA | None | Cysticercosis Ab, IgG by ELISA | 0.0 (Ref: OD ≤ 0.34) | Paraneoplastic antibodies serum: | | ANNA (1–3) | Negative | AGNA-1 | Negative | PCA (1-2) | <1 : 240 Negative | PCA-Tr | <1 : 240 Negative | Amphiphysin | <1 : 240 negative | CRMP-% IgG | <1 : 120 Negative | Striational Ab | 0.0 nmol/L | P/Q type calcium channel Ab | 0.0 nmol/L | 0.0 nmol/L | Ach receptor (muscle binding AB) | 0.0 nmol/L | 0.0 nmol/L | Ach receptor (ganglionic neuronal Ab) | 0.0 nmol/L | Neuronal (V-G) K+ channel Ab | 0.0 nmol/L | Other labs: | | WBC | 6.1 × 109/L | Neutrophil | 73% | Hemoglobin | 15.9 g/dl | Hematocrit | 45.3% | Platelets | 211 × 109/L | MCV | 86 fl | Lymphocyte | 30.70% | Eosinophil | 1.88% | Polys | 62% | Sodium | 136 mEq/L | Potassium | 3.5 mEq/L | Chloride | 105 mEq/L | Bicarbonate | 22 mEq/L | BUN | 15 mg/dl | Creatinine | 0.79 mg/dl | Anion Gap | 9 mEq/L | Vitamin B 12 | 800 pg/ml | Thyroglobulin | 2.0 ng/ml | TSH | 4.016 microIU/ml | CRP | 0.14 mg/L | AST | 22 unit/L | ALT | 21 unit/L | ALP | 61 unit/L | Calcium | 9.6 mg/dl | T-Bili | 0.5 mg/dl | Albumin | 4.4 g/dl | Total protein | 7.5 g/dl |
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