Case Report

Creutzfeldt-Jakob Disease Presenting as Expressive Aphasia and Nonconvulsive Status Epilepticus

Table 1

Laboratory data.

VariableValue

Microbiology
CSFNegative for bacterial growth
Negative for acid fast bacilli (AFB)
Autoimmune panel serum:
Microsomal TPO antibody<0.2 IU/ml
Thyroxine binding globulin19.3 microgram/ml
Anti-TG Ab<0.2 IU/ml
HIV 1/2 PCRNone
Lyme0.07 (Ref: ≤0.99 LIV)
FT AbNon-reactive
West Nile Virus (IgM)None
SSA, 52 (Ro)1 AU/ml
SSA, 60 (Ro)1 AU/ml
Sjogren’s Ab0 AU/ml
ANANone
Cysticercosis Ab, IgG by ELISA0.0 (Ref: OD ≤ 0.34)
Paraneoplastic antibodies serum:
ANNA (1–3)Negative
AGNA-1Negative
PCA (1-2)<1 : 240 Negative
PCA-Tr<1 : 240 Negative
Amphiphysin<1 : 240 negative
CRMP-% IgG<1 : 120 Negative
Striational Ab0.0 nmol/L
P/Q type calcium channel Ab0.0 nmol/L
0.0 nmol/L
Ach receptor (muscle binding AB)0.0 nmol/L
0.0 nmol/L
Ach receptor (ganglionic neuronal Ab)0.0 nmol/L
Neuronal (V-G) K+ channel Ab0.0 nmol/L
Other labs:
WBC6.1 × 109/L
Neutrophil73%
Hemoglobin15.9 g/dl
Hematocrit45.3%
Platelets211 × 109/L
MCV86 fl
Lymphocyte30.70%
Eosinophil1.88%
Polys62%
Sodium136 mEq/L
Potassium3.5 mEq/L
Chloride105 mEq/L
Bicarbonate22 mEq/L
BUN15 mg/dl
Creatinine0.79 mg/dl
Anion Gap9 mEq/L
Vitamin B 12800 pg/ml
Thyroglobulin2.0 ng/ml
TSH4.016 microIU/ml
CRP0.14 mg/L
AST22 unit/L
ALT21 unit/L
ALP61 unit/L
Calcium9.6 mg/dl
T-Bili0.5 mg/dl
Albumin4.4 g/dl
Total protein7.5 g/dl