Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children

Figure 1

MRI scans: (a, e) T2-weighted; (b,f) Fluid Attenuated Inversion Recovery (FLAIR); (c,g) diffusion-weighted imaging; (d,h) apparent diffusion coefficient (ADC) map. The first MRI imaging (a,b,c,d) showed bilateral and symmetrical hyperintensity () inT2, FLAIR and diffusion of the occipital and frontal lobes, cerebellar hemispheres, periventricular white matter, and basal ganglia with low ADC related to cytotoxic edema. After 9 days, control MRI (e, f, g, h) highlighted progressive volume loss of cerebrum with decreased hypersignal and increased ADC in cerebellar hemispheres, fontal and occipital lobes. Hypersignal persists in T2, FLAIR, and diffusion in periventricular white matter with ADC restriction and in basal ganglia without ADC restriction.