The Conundrum of Septic Shock Imitators in Patients with Hematologic Cancers: Case Presentation and Possible Differential Diagnoses

Table 4

Diagnostic criteria for CAPS (from [29]).

Preliminary criteria	Case
(1) Evidence of involvement of ≥3 organs, system and/or tissues	+
(2) Development of clinical manifestation simultaneously or in <1 week	+
(3) Evidence of small vessel occlusion in at least 1 organ or tissue	+
(4) Lab evidences of LAC and/or aCL and aβ2GBPI	n.a.
Definite CAPS
(i) All 4 criteria	−
Probable CAPS
(i) All 4 criteria, 2 organs, system and/or tissues involved	−
(ii) All 4 criteria, except for the lack of lab evidence due to the early death of patients never tested for APS	−
(iii) Criteria 1, 2, and 4	−
(iv) Criteria 1, 3, and 4 and development of a third event between one week and one month after the initial presentation despite anticoagulation	n.a.

n.a: not available.