Case Report

Acute Fatty Liver Disease of Pregnancy in the Second Trimester

Table 1

The Swansea criteria for the diagnosis of acute fatty liver disease of pregnancy. Six or more of the following features need to be present in the absence of another explanation to diagnose AFLP.

SymptomsVomiting
Abdominal pain
Polydipsia/polyuria
Encephalopathy

LaboratoryLeukocytosis
Elevated transaminases
Elevated ammonia
Elevated bilirubin
Elevated urate
Hypoglycemia
Coagulopathy
Renal impairment

ImagingAscites or bright liver on ultrasound

PathologyMicrovesicular steatosis on liver biopsy