Case Report
COVID-19-Induced Fatal Thrombotic Thrombocytopenic Purpura in a Healthy Young Patient
Table 1
Sequential laboratory tests.
| | Biochemical parameters | Reference range | August 11th | August 16th | August 19th |
| | Hemoglobin (g/dL) | 12-16 | 7.5 | 6.4 | 6.5 | | Hematocrit (%) | 37-47 | 21 | 18 | 19 | | Reticulocytes (%) | 0.5-1.5 | 16 | — | 16 | | Mean corpuscular volume (fL) | 80-98 | 91 | 92 | 102 | | Platelet count (103/μ/L) | 150-450 | 9 | 6 | 6 | | Leukocyte count (103/μ/L) | 4.5-11 | 8.7 | 11.5 | 18.6 | | aPTT (seconds) | 25-35 | 19 | 17 | 26 | | PT (seconds) | 11-13 | 11 | 11 | 15 | | INR (IU) | <1.2 | 1.0 | 1.0 | 1.2 | | Fibrinogen (g/L) | 2-4 | 2.01 | — | 3.1 | | AST (U/L) | 10-40 | 38 | — | 484 | | ALT (U/L) | 10-40 | 16 | — | 931 | | Bilirrubin, total (umol/L) | 5.1-17.1 | 34.2 | — | 114.57 | | Bilirrubin, direct (umol/L) | 1.7-5.1 | 13.68 | — | 71.82 | | Bilirrubin, indirect (umol/L) | 3.4-12 | 20.52 | — | 42.75 | | Urea (mmol/L) | 2.9-7.1 | 7.5 | 27.14 | 52.49 | | Creatinine (umol/L) | 44-97 | 61.89 | 88.42 | 106.1 | | LDH (U/L) | 80-225 | 849 | 2356 | 3711 | | SARS-CoV-2 test result | Negative | — | Negative (antigen) | Positive (nasal swab PCR) |
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ALT: alanine aminotransferase; aPTT: activated partial thromboplastin time; AST: aspartate aminotransferase; INR: international normalized ratio; LDH: lactate dehydrogenase; PT: prothrombin time.
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