A Rare Cause of a Rare Disorder: E. coli-Induced Purpura Fulminans Secondary to Urinary Tract Infection

Table 1

Laboratory values upon initial presentation to our facility. Of note, patient remained on continuous heparin infusion during time of lab results.

Lab tests	Hospital day 1 (outlying hospital)	Hospital day 1 (this hospital)	Hospital day 5 (this hospital)	Units (normal range)
Hemoglobin	12.8	11.5	10.6	11.6-15 g/dL
Hematocrit	39.3	35.6	33.7	35.5-44.9%
White blood cell count	13.8 with 13% bands	55.96	19.9	3.4-10.8 K/mm^3
Platelets	203 (nadir 73)	92	288	150-379 K/mm^3
Sodium	140	143	137	135-145 mmol/L
Potassium	3.6	3.9	4.7	3.5-5 mmol/L
Chloride	110	111	104	95-105 mmol/L
Bicarbonate	24	24	24	23-29 mmol/L
Blood urea nitrogen	20	21	8	5-20 mg/dL
Creatinine	1.5	0.66	0.67	0.61.2 mg/dL
Albumin	4	2.7	2.9	3.5-4.8 g/dL
Aspartate aminotransferase	26	227	124	0-40 U/L
Alanine transferase	20	114	74	0-32 U/L
Lactate	6.8	1.5	2.2	Mmol/L
Creatinine phosphokinase		5976	1002	22-198 U/L
Activated partial thromboplastin time (PTT)		55.9 (on heparin drip)	65.5 (on heparin drip)	25-35 seconds
Prothrombin time (PT)		14.7	14.3	Seconds
International normalized ratio (INR)		1.2	1.15	N/a
D-dimer		13.95	3.66	<0.5 μg/mL
Total bilirubin		0.5	0.2	0.0-1.2 mg/dL
Fibrinogen		622	619	200-400 mg/dL
Haptoglobin			284	41-165 mg/dL
Antinuclear antibody (ANA) screen			Positive (RNP ab)	0.2 - 0.9 AU/mL
p/c-Antineutrophil cytoplasmic antibodies (ANCA)			0.2	<0.4 (negative)
Complement factors 3, 4			116, 21	82-193 mg/dL, 15-57 mg/dL
Protein S, functional:			79%	60-123%
Protein C, functional:			174%	70-130%

Indicates lab value either not drawn or not available due to lab error.