|
| Conditions associated with gingival hyperplasia | Features |
|
| Autosomal recessive | |
| I-cell disease (Mucolipidosis II) | Mental and physical retardation; appears prior to eruption of primary teeth |
| Ramon Syndrome | Gingival fibromatosis, hypertrichosis, cherubism, mental retardation, and seizures |
| Juvenile hyaline fibromatosis (Murray-Peretic-Drescher syndrome) | Multiple hyaline fibromas, white papules on the skin, flexion contractures, osteolytic bone lesions, and gingival fibromatosis |
| Alpha-Mannosidosis | A type of oligosaccharidosis, delayed early motor development, mild hypotonia, hypoplastic bones, macroglossia, hepatosplenomegaly, and gingival enlargement |
| Donohue syndrome (Leprechaunism) | Failure to thrive, unusual facies, facial hirsutism, retarded bone age, and insulin resistance with glucose intolerance and hyperinsulinemia |
| Cross syndrome | Hypopigmentation, microphthalmia, mental retardation, athetosis, and gingival fibromatosis |
| Hornova-Dluhosova syndrome | Oral and conjunctival amyloidosis and mental retardation |
|
| Autosomal dominant | |
| Zimmerman-Laband syndrome | Gingival fibromatosis, ear, bone, nail defects, hepatosplenomegaly |
| Rutherford syndrome | Gingival fibromatosis and corneal dystrophy, failure of tooth eruption |
| Jones syndrome | Gingival fibromatosis with sensorineural hearing loss |
|
| Other | |
| Borronedermato-cardio-skeletal syndrom (Autosomal recessive/X-linked recessive) | Coarse facies, thick skin, acne conglobata, gingival enlargement, osteolysis, camptodactyly, and mitral valve prolapsed |
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