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Case Reports in Dentistry
Volume 2012 (2012), Article ID 840167, 3 pages
http://dx.doi.org/10.1155/2012/840167
Case Report

Familial Progressive Hyperpigmentation: A Case Report

1Department of Oral Pathology and Microbiology, Terna Dental College and Hospital, Sector No. 22, Nerul 400706, India
2Department of Periodontics, Terna Dental College and Hospital, Sector No. 22, Nerul 400706, India
3Department of Oral Pathology, Terna Dental College and Hospital, Sector No. 22, Nerul 400706, India

Received 19 January 2012; Accepted 28 February 2012

Academic Editors: P. G. Arduino, Y.-K. Chen, and A. Epivatianos

Copyright © 2012 Monica Yadav et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Familial progressive hyperpigmentation (FPH) is a rare genodermatosis characterized by hyperpigmented patches in the skin and mucous membranes, present in early infancy, and increase in size and number with age. The genetic basis for FPH remains unknown. We report an unusual case of familial progressive hypermelanosis in a 17-year-old male patient with family history, who presented with a peculiar progressive oral pigmentation disorder. Diagnosis was confirmed by a series of hematological, biochemical, and histopathological investigations. Our paper stresses the need for the dentist to be aware of the systemic conditions that can also manifest in the oral cavity.