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Case Reports in Dentistry
Volume 2013 (2013), Article ID 726815, 5 pages
Case Report

Melanotic Neuroectodermal Tumor of Infancy in the Maxilla

1Department of Oral Surgery, School of Dentistry, University of São Paulo, Avenida Prof. Lineu Prestes 2227, Butantã, 05508-000 São Paulo, SP, Brazil
2Residency Program in Oral and Maxillofacial Surgery at Conjunto Hospitalar do Mandaqui, São Paulo, SP, Brazil
3Department of Oral Pathology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil
4Department of Oral and Maxillofacial Surgery, Conjunto Hospitalar do Mandaqui, São Paulo, SP, Brazil

Received 28 June 2013; Accepted 24 July 2013

Academic Editors: A. Kasaj and C. Landes

Copyright © 2013 Daniel Falbo Martins de Souza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Melanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increasing swelling in the left cheek. MNTI was diagnosed in this case following tomography and biopsy. The patient's histological and immunohistochemical profile indicated a remarkable combination of neural, melanocytic, and epithelial cell differentiation. One year following tumor excision, a follow-up examination revealed that the child exhibited no tumor recurrence. Approximately 260 cases of MNTI have been reported since this type of tumor was first described. In the present case, early diagnosis minimized the difficulties and risks associated with treatment and facilitated an optimal outcome. Despite complete surgical excision, careful followup is recommended. In addition, maxillary functional orthopedics and reconstruction may be necessary in cases of MNTI.