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Case Reports in Dentistry
Volume 2014, Article ID 864512, 4 pages
Case Report

Giant Cell Fibroma of Tongue: Understanding the Nature of an Unusual Histopathological Entity

1Department of Oral Pathology and Microbiology, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh 482001, India
2Department of Oral Pathology and Microbiology, Maitri College of Dentistry and Research Center, Durg, Chattisgarh 490020, India
3Department of Prosthodontics, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh 482001, India
4Department of Prosthodontics, Rungta College of Dental Sciences and Research, Bhilai, Chattisgarh 490024, India
5Department of Prosthodontics, Government College of Dentistry, Indore, Madhya Pradesh 452001, India
6Department of Prosthodontics, Shri Aurbindo Institute of Medical Sciences, Indore, Madhya Pradesh 453555, India
7Department of Prosthodontics, M.N.D.A.V Dental College and Hospital, Solan, Himachal Pradesh 173223, India

Received 10 September 2013; Accepted 17 December 2013; Published 9 January 2014

Academic Editors: Y.-K. Chen, J. H. Jeng, P. Lopez Jornet, and L. Manuel Junquera Gutierrez

Copyright © 2014 Wanjari Ghate Sonalika et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Giant cell fibroma (GCF) is a rare case with unique histopathology. It belongs to the broad category of fibrous hyperplastic lesions of the oral cavity. It is often mistaken with fibroma and papilloma due to its clinical resemblance. Only its peculiar histopathological features help us to distinguish it from them. The origin of the giant cell is still controversial. Data available is very sparse to predict the exact behavior. Hence, we report a case of GCF of tongue in a 19-year-old male. Special emphasis is given to understand the basic process of development of the lesion, nature of giant cells, and also the need for formation of these peculiar cells. Briefly, the differential diagnosis for GCF is tabulated.