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Case Reports in Dentistry
Volume 2015, Article ID 292819, 5 pages
http://dx.doi.org/10.1155/2015/292819
Case Report

Cystic Odontoma in a Patient with Hodgkin’s Lymphoma

1Bioscience and Oral Diagnosis Department, Institute of Science and Technology, Universidade Estadual Paulista (UNESP), School of Dentistry, 12247-004 São José dos Campos, SP, Brazil
2Oral Pathology Department, Ribeirão Preto Dental School, University of São Paulo, 14040-900 Ribeirão Preto, SP, Brazil
3Pediatric Dentistry Department, Institute of Science and Technology, Universidade Estadual Paulista (UNESP), School of Dentistry, 12247-004 São José dos Campos, SP, Brazil
4Pediatric Oncology, “Fabiana Macêdo de Moraes” Children Treatment Center, 12244-010 São José dos Campos, SP, Brazil

Received 18 April 2015; Accepted 9 August 2015

Academic Editor: Luis M. J. Gutierrez

Copyright © 2015 Victor Costa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cystic odontoma is a rare entity, which is characterized by the association of a cyst with complex/compound odontoma. The aim of this study was to report the case of a 5-year-old male patient diagnosed previously with Hodgkin’s lymphoma and treated successfully with chemotherapy and radiotherapy, who developed a mandibular odontogenic lesion. Physical examination revealed a swelling on the right side of the mandible. Radiographically, a well-defined radiolucent area surrounded by radiopaque material was observed. An incisional biopsy was performed and microscopic analysis showed a cystic lesion consisting of an atrophic epithelium comprising 2-3 cell layers and the absence of inflammation in the cystic capsule. The cyst was decompressed and the lesion was removed after 3 months of follow-up. Microscopic analysis of the surgical specimen showed a cystic hyperplastic epithelium surrounded by an intense chronic inflammatory cell infiltrate, which was in close contact with mineralized tissue resembling dentin and cementum. The final diagnosis was cystic odontoma. Since chemotherapy can affect the growth and development of infant teeth, a relationship between chemotherapy-associated adverse events and cystic odontoma is suggested in the present case.