Case Report

Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient

Table 1


Study (year of publication) of casesAge (years)GenderTumor locationSize (cm)Immunohistochemical markers

(1) Maeda et al. (1989) [10]137MUpper lip0.7 × 0.8Vimentin+, desmin+, factor VIII+ S-100-, NSE+
(2) Maeda and Osaki (1989) [11]149FCheek2.0 × 2.0Vimentin+, desmin+, factor VIII+ S-100-
(3) Anastassov and Damme (1995) [12]151MUpper lip1.5 × 1.0SMA+, factor VIII-
(4) Toida et al. (2000) [13]110MLower lip2.0 × 1.5SMA+, S-100-
(5) Marden et al. (2004) [14]125MTongue3.2 × 3.0 × 1.2SMA+, CD34+, CD31+
(6) Manor et al. (2007) [15]139MBuccal mucosa3.5 × 3.3 × 2.0SMA+
(7) Scheper et al. (2007) [16]167MPalate5.0 × 5.0SMA+
(8) Suresh et al. (2007) [17]151FMandible1.7 × 1.5SMA+, vimentin+, CD34-, S-100-
(9) Cepeda et al. (2008) [18]539
27
43
36
48
F
F
F
M
M
Retromolar area
Mandible
Lower lip
Upper lip
Upper lip
0.9 × 0.6 × 1.0
1.4 × 1.3 × 1.0
0.7 × 0.5 × 0.4
1.5 × 1.0 × 1.0
1.7 × 1.0 × 1.0
SMA+, vimentin+, desmin+, CD34-, S-100-
SMA+, vimentin+, desmin+, CD34-, S-100-
SMA+, vimentin+, desmin+, CD34-, S-100-
SMA+, vimentin+, desmin+, CD34-, S-100-
SMA+, vimentin+, desmin+, CD34-, S-100-
(10) Keerthi et al. (2009) [19]132MCheek4.5 × 4.0SMA+
(11) Grossman et al. (2009) [20]135FPalate1.0 × 1.0 × 0.5SMA+, vimentin+, desmin+, S-100-, HHF-35+, AE1/AE3-
(12) Kim et al. (2010) [21]12 monthsNot reportedTongue2.5 × 2.0SMA+, vimentin-, desmin+, S-100-
(13) Kim et al. (2010) [22]151MBuccal space3.0 × 3.0SMA+, CD34-, S-100-
(14) Nonaka et al. (2011) [23]139MTongue2.0 ∅SMA+
(15) Gueiros et al. (2011) [24]354
66
54
M
M
M
Lower lip
Upper lip
Upper lip
1.0 × 1.0
Not reported
0.8 × 0.5 × 0.5
SMA+, desmin+, CD34+, S-100+, HHF-35+, D2-40-
SMA+, desmin+, CD34+, S-100-, HHF-35+, D2-40-
SMA+, desmin+, CD34+, S-100+, HHF-35+, D2-40-
(16) Patil et al. (2011) [25]157MLower left back tooth region3.0 × 1.5 × 1.0SMA+, vimentin+, desmin+, S-100-
(17) Menditti et al. (2012) [26]114MLingual mucosa of mandible1.0/2.0 ∅SMA+
(18) Eley et al. (2012) [27]139MPalate2.0 ∅Desmin+, actin+
(19) Liu et al. (2014) [28]1462
49
36
51
49
10
30
20
60
34
58
18
19
47
F
M
F
F
F
F
F
M
M
M
M
M
M
M
Buccal mucosa
Buccal mucosa
Buccal mucosa
Buccal mucosa
Palate
Mandible
Buccal mucosa
Gingiva
Palate
Palate
Lip
Palate
Tongue
Buccal mucosa
1.5 ∅
2.0 ∅
2.0 ∅
1.0 ∅
1.0 ∅
3.5 ∅
3.0 ∅
2.5 ∅
1.5 ∅
1.0 ∅
6.0 ∅
3.5 ∅
3.5 ∅
2.0 ∅
SMA+, vimentin+, desmin+, CD34+ in all cases
S-100+ only in 3 cases (not specified)
(20) Tsuji et al. (2014) [3]179MPalate1.5 × 1.5SMA+, desmin+
(21) Ishikawa et al. (2014) [29]151MTongue1.1 ∅SMA+, vimentin+, desmin+, CD34-, S-100-, HHF-35+
(22) Ranjan and Singh (2014) [30]145FGingiva3.0 × 3.0SMA+
(23) Inaba et al. (2015) [31]145FCheekNot reportedSMA+, factor VIII+
(24) Osano et al. (2015) [9]145MCheek2.0 ∅SMA+, vimentin+, desmin+, CD34-, S-100-
(25) Arpağ et al. (2016) [32]225
55
M
F
Gingiva
Gingiva
0.5 × 0.5
1.5 × 2.0
SMA+
SMA+
(26) Bajpai et al. (2016) [33]139MGingiva3.0 × 3.0SMA+, vimentin+, desmin+
(27) Hassona et al. (2017) [4]152FUpper lipNot reportedSMA+
(28) Rawal and Rawal (2017) [8]170MPalate2.0 × 1.5SMA+
(29) Matiakis et al. (2018) [7]151MLabial mucosa of the upper lip0.8 ∅SMA+, h-caldesmon+
(30) Aitken-Saavedra et al. (2018) [34]14Total mean 45.2
Lower lip
Lower lip
Lower lip
Lower lip
Upper lip
Upper lip
Upper lip
Buccal mucosa
Buccal mucosa
Buccal mucosa
Buccal mucosa
Soft palate
Soft palate
Hard palate
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
Not reported
SMA+, AE1/AE3-, CD68-, desmin+, S-100- in all cases
CD34+ only in 10 cases (not specified)
Case report117FCheek1.5 × 1.0SMA+, vimentin+, desmin+, CD34+