Parathyroidectomy Resolves Tooth Discoloration: A New Presenting Sign of Hyperparathyroidism?
Table 1
Patient’s characteristics at baseline and follow-up.
Variable
Normal range
At PHPT diagnosis†
Baseline‡
FU 1 month
FU 6 months
FU 12 months
Age (yrs)
54
59
—
—
60
Biochemistry
PTH (ng/L)
6.5-36.8
58.2
72.0
48.3
49.9
64.3
Ca total (mmol/L)§
2.10-2.55
2.58
2.76
2.32
2.43
2.37
Ca2+ (mmol/L)§§
1.19-1.29
1.36
1.36
1.18
1.15
1.19
u-Ca (mmol/24 h)
2.5-7.5
8.62
8.62
na
na
3.93
p-P (mmol/L)
0.87-1.45
0.91
0.82
na
1.04
0.97
u-P (mmol/24 h)
12.9-42
15.6
19.5
na
na
17.0
25-OH vitamin D (nmol/L)
>75
78
82
na
na
87
Bone mineral density (BMD)
Lumbar spine L2-L4 score (SD)
-1.6
-1.8
na
na
-1.9
Total femur score (SD)
-1.4
-2.0
na
na
-2.0
Oral assessment
Teeth ()
27
27
27
27
27
Front upper incisors (vita scale)
A2
C2
C2
A2
A2
Lateral upper incisors (vita scale)
A1
C1
C1
A2-A1
A1
Front lower incisors (vita scale)
A2
C2
C2
A2
A2
Lateral lower incisors (vita scale)
A2
C2
C2
A2
A2
Torus elevation (mm)
na
4
4
4
4
PHPT = primary hyperparathyroidism; FU = follow-up; na = not available/not assessed. †PHPT diagnosis was made 5 yrs prior to surgery. ‡Baseline assessment was performed two months prior to surgery. §Total serum calcium, not adjusted for albumin. §§Ionized calcium, collected and measured according to the current recommendations.
