Oral Lichen Planus and Polycythemia: Possible Association

Table 2

The WHO diagnosis criteria for PV (2016) and the diagnosis retained.

WHO diagnostic criteria for PV (2016)	Our patient	Final diagnosis
(1) Major criteria; (a) Hemoglobin:16.5 g/dL in men; hemoglobin: 16.0 g/dL in women; Or hematocrit: 49% in men; hematocrit: 48% in women; Or increased red cell mass (RCM); (b) BM biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic, and megakaryocytic proliferation with pleomorphic, mature megakaryocytes (differences in size); (c) Presence of JAK2 (V617F) or JAK2 exon 12 mutation	Hb =19 g/dL and Ht =54.4% BM biopsy not realized because of bleeding risk; Absence of JAK2 (V617F) mutation	Polycythemia vera (PV) ruled out; Polycythemia secondary to chronic hypoxia retained
(2) Minor criteria; (i) Subnormal serum erythropoietin level	Increased serum erythropoietin level (109 mIU/mL)
Diagnosis of polycythaemia vera (PV) requires meeting either all 3 major criteria or the first 2 major criteria and the minor criterion