Case Reports in Dentistry / 2021 / Article / Tab 1 / Case Report
Medication-Related Osteonecrosis of the Jaw Spontaneously Occurred in a Patient with Chronic Myelogenous Leukemia Only by Imatinib: A Report of a Rare Case Table 1 Reported MRONJ cases related to imatinib [
17 ā
19 ].
No. Study (yr) Age (yr)/gender Disease Period of imatinib treatment (mo) Antiresorptive agent Trigger event Stage Treatment Clinical outcome 1 Nicolatou-Galitis et al. (2013) [17 ] 71/M CML 19 Alendronate Zoledoronate Denosumab Tooth extraction II Antibiotic Improved 2 Viviano et al. (2017) [19 ] 72/M GIST 22 None Tooth extraction II Antibiotic Unknown 3 Mohamed et al. (2018) [18 ] 81/F CLL 13 Alendronate Denosumab Tooth extraction II Surgery Healed 4 Present case (2020) 52/F CML 111 None None II Surgery Healed
Abbreviations: MRONJ: medication-related osteonecrosis of the jaw; F: female; M: male; CML: chronic myelogenous leukemia; GIST: gastrointestinal stromal tumor; CLL: chronic lymphocytic leukemia.