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Case Reports in Dermatological Medicine
Volume 2013, Article ID 370361, 3 pages
Case Report

Perforating Disseminated Necrobiosis Lipoidica Diabeticorum

Department of Dermatology and Venereology, Medical University Sofia, Sofia, Bulgaria

Received 30 November 2012; Accepted 14 January 2013

Academic Editors: H. Dobrev and E. Schmidt

Copyright © 2013 Paula Lozanova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Perforating necrobiosis lipoidica is a very rare clinical variant which consists of degeneration and transepidermal elimination of the collagen with few cases reported in the literature. In two-thirds of the patients it associates with diabetes, with no relation with the glucose control. We present a 42-year-old female patient with a 7-year history of diabetes on insulin therapy, referred to our clinic with a 3-year history of multiple asymptomatic firm plaques disseminated on the upper and lower extremities. The clinical and histological findings proved the diagnosis of perforating necrobiosis lipoidica.