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Case Reports in Dermatological Medicine
Volume 2013, Article ID 424797, 5 pages
Case Report

Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature

1Department of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, Italy
2Department of Biomorphological and Functional Sciences, Federico II University, 80131 Naples, Italy

Received 28 November 2012; Accepted 27 December 2012

Academic Editors: B. Kumar and J. Y. Lee

Copyright © 2013 Massimiliano Scalvenzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.