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Case Reports in Dermatological Medicine
Volume 2013, Article ID 469505, 4 pages
http://dx.doi.org/10.1155/2013/469505
Case Report

Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers in Young Patients

1Department of Dermatology, Pontchaillou University Hospital, 2 Rue Henri Le Guilloux, 35033 Rennes, France
2Department of Vascular Surgery, Pontchaillou University Hospital, 2 Rue Henri Le Guilloux, 35033 Rennes, France
3Department of Dermatopathology, Sart-Tilman University Hospital, B-4000 Liège, Belgium
4Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium

Received 19 August 2013; Accepted 10 September 2013

Academic Editors: N. Oiso and T. Yamamoto

Copyright © 2013 Sophie Ronceray et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ehlers-Danlos syndrome type VIII (EDS-VIII) is a very rare autosomal dominant disease characterized by early-onset periodontitis associated with features of Ehlers-Danlos syndrome. We report a 32-year-old man whose chronic leg ulcer led to the diagnosis of EDS-VIII. He had severe periodontitis with complete loss of permanent teeth and skin fragility with thin skin, atrophic scars, and brownish atrophic pretibial plaques. Leg ulcer is not a prominent feature of EDS-VIII. We suggest adding EDS-VIII to the list of rare diseases accounting for chronic leg ulcers, if this case report prompts others to report leg ulcers associated with EDS-VIII.