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Case Reports in Dermatological Medicine
Volume 2013, Article ID 906426, 5 pages
http://dx.doi.org/10.1155/2013/906426
Case Report

Unusual Clinical Presentation of Cutaneous Angiosarcoma Masquerading as Eczema: A Case Report and Review of the Literature

1Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA
2Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
3Department of Hematology and Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
4Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
5Department of Dermatology, Loyola University Medical Center, Maywood, IL 60153, USA

Received 5 August 2013; Accepted 4 September 2013

Academic Editors: J. C. Szepietowski and J. A. Tschen

Copyright © 2013 Nhat Q. Trinh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. W. Weiss, J. R. Goldblum, and A. L. Folpe, Enzinger and Weiss's Soft Tissue Tumors, Mosby, St. Louis, Mo, USA, 2007.
  2. A. Selim, A. Khachemoune, and N. A. Lockshin, “Angiosarcoma: a case report and review of the literature,” Cutis, vol. 76, no. 5, pp. 313–317, 2005. View at Google Scholar · View at Scopus
  3. M. B. Morgan, M. Swann, S. Somach, W. Eng, and B. Smoller, “Cutaneous angiosarcoma: a case series with prognostic correlation,” Journal of the American Academy of Dermatology, vol. 50, no. 6, pp. 867–874, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. B. A. Guadagnolo, G. K. Zagars, D. Araujo, V. Ravi, T. D. Shellenberger, and E. M. Sturgis, “Outcomes after definitive treatment for cutaneous angiosarcoma of the face and scalp,” Head and Neck, vol. 33, no. 5, pp. 661–667, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Ogawa, K. Takahashi, Y. Asato et al., “Treatment and prognosis of angiosarcoma of the scalp and face: a retrospective analysis of 48 patients,” The British Journal of Radiology, vol. 85, no. 1019, pp. e1127–e1133, 2012. View at Publisher · View at Google Scholar
  6. R. J. Young, N. J. Brown, M. W. Reed, D. Hughes, and P. J. Woll, “Angiosarcoma,” The Lancet Oncology, vol. 11, no. 10, pp. 983–991, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Mentzel, H. Kutzner, and U. Wollina, “Cutaneous angiosarcoma of the face: clinicopathologic and immunohistochemical study of a case resembling rosacea clinically,” Journal of the American Academy of Dermatology, vol. 38, no. 5, pp. 837–840, 1998. View at Google Scholar · View at Scopus
  8. J. M. Shehan and I. Ahmed, “Angiosarcoma arising in a lymphedematous abdominal pannus with histologic features reminiscent of Kaposi's sarcoma: report of a case and review of the literature,” International Journal of Dermatology, vol. 45, no. 5, pp. 499–503, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. T. E. Knight, H. M. Robinson Jr., and B. Sina, “Angiosarcoma (angioendothelioma) of the scalp. An unusual case of scarring alopecia,” Archives of Dermatology, vol. 116, no. 6, pp. 683–686, 1980. View at Publisher · View at Google Scholar · View at Scopus
  10. Z. Pan, D. Albertson, A. Bhuller, B. Wang, J. M. Shehan, and D. P. Sarma, “Angiosarcoma of the scalp mimicking a sebaceous cyst,” Dermatology Online Journal, vol. 14, no. 6, article 13, 2008. View at Google Scholar · View at Scopus
  11. L. I. Aguila and J. L. Sánchez, “Angiosarcoma of the face resembling rhinophyma,” Journal of the American Academy of Dermatology, vol. 49, no. 3, pp. 530–531, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. H. F. Köhler, R. I. Neves, E. R. Brechtbühl, N. V. M. Granja, M. K. Ikeda, and L. P. Kowalski, “Cutaneous angiosarcoma of the head and neck: report of 23 cases from a single institution,” Otolaryngology—Head and Neck Surgery, vol. 139, no. 4, pp. 519–524, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. C. A. Holden, M. F. Spittle, and E. W. Jones, “Angiosarcoma of the face and scalp, prognosis and treatment,” Cancer, vol. 59, no. 5, pp. 1046–1057, 1987. View at Google Scholar · View at Scopus
  14. T. M. Pawlik, A. F. Paulino, C. J. McGinn et al., “Cutaneous angiosarcoma of the scalp: a multidisciplinary approach,” Cancer, vol. 98, no. 8, pp. 1716–1726, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Kitagawa, I. Tanaka, T. Takemura, O. Matsubara, and T. Kasuga, “Angiosarcoma of the scalp: report of two cases with fatal pulmonary complications and a review of Japanese autopsy registry data,” Virchows Archiv, vol. 412, no. 1, pp. 83–87, 1987. View at Google Scholar · View at Scopus
  16. M. Nomura, Y. Nakaya, K. Saito et al., “Hemopneumothorax secondary to multiple cavitary metastasis in angiosarcoma of the scalp,” Respiration, vol. 61, no. 2, pp. 109–112, 1994. View at Google Scholar · View at Scopus
  17. N. Naka, M. Ohsawa, Y. Tomita et al., “Prognostic factors in angiosarcoma: a multivariate analysis of 55 cases,” Journal of Surgical Oncology, vol. 61, no. 3, pp. 170–176, 1998. View at Google Scholar
  18. R. J. Mark, J. C. Poen, L. M. Tran, Y. S. Fu, and G. F. Juillard, “Angiosarcoma: a report of 67 patients and a review of the literature,” Cancer, vol. 77, no. 11, pp. 2400–2406, 1996. View at Publisher · View at Google Scholar
  19. A. Kacker, C. R. Antonescu, and A. R. Shaha, “Multifocal angiosarcoma of the scalp: a case report and review of the literature,” Ear, Nose and Throat Journal, vol. 78, no. 4, pp. 302–305, 1999. View at Google Scholar · View at Scopus
  20. W. M. Lydiatt, A. R. Shaha, and J. P. Shah, “Angiosarcoma of the head and neck,” The American Journal of Surgery, vol. 168, no. 5, pp. 451–454, 1994. View at Publisher · View at Google Scholar · View at Scopus
  21. W. H. Morrison, R. M. Byers, A. S. Garden, H. L. Evans, K. K. Ang, and L. J. Peters, “Cutaneous angiosarcoma of the head and neck. A therapeutic dilemma,” Cancer, vol. 76, no. 2, pp. 319–327, 1995. View at Publisher · View at Google Scholar
  22. J. R. Ward, S. J. Feigenberg, N. P. Mendenhall, R. B. Marcus Jr., and W. M. Mendenhall, “Radiation therapy for angiosarcoma,” Head and Neck, vol. 25, no. 10, pp. 873–878, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Romanyshyn, S. Wolden, N. Caria et al., “Radiation therapy in the treatment of angiosarcoma of the head and neck,” International Journal of Radiation Oncology Biology Physics, vol. 78, no. 3, pp. S483–S483, 2010. View at Google Scholar
  24. J. Glickstein, M. E. Sebelik, and Q. Lu, “Cutaneous angiosarcoma of the head and neck: a case presentation and review of the literature,” Ear, Nose and Throat Journal, vol. 85, no. 10, pp. 672–674, 2006. View at Google Scholar · View at Scopus
  25. V. B. Patel and T. W. Speer, “Successful treatment of an angiosarcoma of the nose with radiation therapy,” Case Reports in Oncology, vol. 5, no. 3, pp. 570–575, 2012. View at Publisher · View at Google Scholar
  26. S. Gkalpakiotis, P. Arenberger, O. Vohradnikova, and M. Arenbergerova, “Successful radiotherapy of facial angiosarcoma,” International Journal of Dermatology, vol. 47, no. 11, pp. 1190–1192, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. N. Penel, A. Lansiaux, and A. Adenis, “Angiosarcomas and taxanes,” Current Treatment Options in Oncology, vol. 8, no. 6, pp. 428–434, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Penel, B. N. Bui, J. Bay et al., “Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX study,” Journal of Clinical Oncology, vol. 26, no. 32, pp. 5269–5274, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Agulnik, S. Okuno, M. Von Mehren et al., “An open-label multicenter phase II study of bevacizumab for the treatment of angiosarcoma,” Journal of Clinical Oncology, vol. 27, supplement 15, Article ID 10522, 2009. View at Google Scholar
  30. S. George, P. Merriam, R. G. Maki et al., “Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas,” Journal of Clinical Oncology, vol. 27, no. 19, pp. 3154–3160, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. R. G. Maki, D. R. D'Adamo, M. L. Keohan et al., “Phase II study of sorafenib in patients with metastatic or recurrent sarcomas,” Journal of Clinical Oncology, vol. 27, no. 19, pp. 3133–3140, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. M. S. Park, V. Ravi, and D. M. Araujo, “Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor,” Current Opinion in Oncology, vol. 22, no. 4, pp. 351–355, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. P. S. Thong, K. W. Ong, N. S. Goh et al., “Photodynamic-therapy-activated immune response against distant untreated tumours in recurrent angiosarcoma,” The Lancet Oncology, vol. 8, no. 10, pp. 950–952, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. I. Jin, M. Yuji, N. Yoshinori, K. Makoto, and M. Mikio, “Anti-tumor effect of PDT using Photofrin in a mouse angiosarcoma model,” Archives of Dermatological Research, vol. 300, no. 4, pp. 161–166, 2008. View at Publisher · View at Google Scholar · View at Scopus