Unusual Clinical Presentation of Cutaneous Angiosarcoma Masquerading as Eczema: A Case Report and Review of the Literature

Table 1

Overview of cutaneous angiosarcoma.

Location	Commonly found on the head and neck; Predominately the scalp and cheek region
Age	Generally occurs in the elderly population
Sex	More common in males
Poor prognostic factors	Presence of metastasis; High mitotic count	Size of lesion >5 cm; High histological grade
Typical appearances	Raised purplish-red papules; Bruise-like lesions	Rosacea-like lesions
Differential diagnosis	Rhinophyma; Sebaceous cysts; Eczema	Kaposi sarcoma; Scarring alopecia
Treatment options	Surgical excision
	Recommend excision with wide negative margins or with postoperative radiotherapy
	Caveat: lesions >5 cm are difficult to completely resect
	Radiotherapy
	Recommend wide treatment fields with doses of >50 Gy
	Caveat: underestimation of the margins of tumor growth
	Chemotherapy
	Promising results shown with taxanes, bevacizumab, sunitinib, and sorafenib
	Caveat: toxicity levels
	Photodynamic therapy
	Further research required to characterize the molecular mechanisms and optimize administration of this therapy
	Caveat: depth of penetration