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Case Reports in Dermatological Medicine
Volume 2014 (2014), Article ID 251423, 3 pages
http://dx.doi.org/10.1155/2014/251423
Case Report

Reactivation of Cutaneous Leishmaniasis after Renal Transplantation: A Case Report

1Department of Dermatology, Tehran University of Medical Sciences, Razi Hospital, Vahdat Islamic Square, Tehran 1199663911, Iran
2Department of Pathology, Tehran University of Medical Sciences, Razi Hospital, Vahdat Islamic Square, Tehran 1199663911, Iran

Received 30 September 2013; Accepted 12 December 2013; Published 16 January 2014

Academic Editors: H. Dobrev, H. Silm, and M. Vaccaro

Copyright © 2014 Hossein Mortazavi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 45-year-old man with reactivation of previously existing and subsiding cutaneous leishmaniasis on his wrist and lower leg (shin) after renal transplantation was admitted to our dermatology service on March 2008. He presented to us with two huge tumoral and cauliflower-like lesions. Skin smear and histopathology of skin showed leishman bodies and confirmed the diagnosis. After renal transplantation, he received cyclosporine plus prednisolone to induce immunosuppression and reduce the probability of transplant rejection. After immunosuppressive therapy, reactivation of cutaneous leishmaniasis with the above presentation took place. The patient responded to 800 mg/day intravenous sodium stibogluconate for 3 weeks plus local cryotherapy. Systemic plus local therapy along with reducing the doses of immunosuppressive drugs led to improvement of lesions. Reactivation of leishmaniasis after immunosuppression has been rarely reported.