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Case Reports in Dermatological Medicine
Volume 2014, Article ID 650714, 3 pages
Case Report

A Gigantic Anogenital Lesion: Buschke-Lowenstein Tumor

Department of Medicine, Allegheny General Hospital, 420 East North Avenue, Allegheny Health Network, Pittsburgh, PA 15212, USA

Received 11 July 2014; Accepted 17 October 2014; Published 6 November 2014

Academic Editor: Xing-Hua Gao

Copyright © 2014 Rikinder Sandhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It is a neoplasm of the anogenital region which has benign appearance on histopathology but is locally destructive. It carries a high recurrence rate and a significant potential for malignant transformation. Human papilloma virus has been implicated as an etiologic agent for this tumor. Since this disease is rare and no controlled studies exist, radical excision of this anogenital lesion is generally recommended as the first line therapy and close vigilance and followup are essential. We have discussed an overview of etiopathogenesis, clinical presentation, diagnosis, and management of this uncommonly encountered disease.