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Case Reports in Dermatological Medicine
Volume 2015, Article ID 934247, 4 pages
Case Report

Idiopathic Thrombocytopenic Purpura Misdiagnosed as Hereditary Angioedema

1Department of Otorhinolaryngology, Head and Neck Surgery, Køge Hospital, Lykkebaekvej 1, 4600 Køge, Denmark
2HAE Centre Denmark, Department of Dermatology and Allergy Centre, Odense University Hospital, Sdr. Boulevard 29, Entrance 142, 5000 Odense C, Denmark

Received 30 October 2015; Revised 5 December 2015; Accepted 15 December 2015

Academic Editor: Michihiro Hide

Copyright © 2015 Michelle Fog Andersen and Anette Bygum. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hereditary angioedema is a rare, but potentially life-threatening genetic disorder that results from an autosomal dominant trait. It is characterized by acute, recurrent attacks of severe local edema, most commonly affecting the skin and mucosa. Swelling in hereditary angioedema patients does however not always have to be caused by angioedema but can relate to other concomitant disorders. In this report we are focusing on misdiagnosis in a patient with known hereditary angioedema, whose bleeding episode caused by idiopathic thrombocytopenic purpura was mistaken for an acute attack of hereditary angioedema. The case illustrates how clinicians can have difficulties in handling patients with rare diseases, especially in the emergency care setting.