Case Report

Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum

Table 1

Description of cases reported of pyoderma gangrenosum with peripheral ulcerative keratitis (PUK). Literature review.

AuthorsGenderAgePUKAssociationTherapyResponse to therapy

Bouchard et al. [5]Male37BilateralChronic myelogenous leukaemiaSystemic corticosteroidsComplete response

Bishop and Tullo [6]Female59Left eyeMonoarticular arthritisCyclophosphamide and systemic corticosteroidsImproved but with intermittent flares of ocular diseases

Bishop and Tullo [6]Male56Right eyeLeukocytoclastic vasculitisSystemic corticosteroidsImproved but with recurrence of ocular disease

Wilson et al. [7]Female60Left eyeRheumatoid arthritis and leukocytoclastic vasculitisCyclosporine A and systemic corticosteroidsImproved but with intermittent flares of ocular and skin diseases

Brown et al. [8]Male54Right eyeChronic obstructive pulmonary disease and
diabetes mellitus
Systemic corticosteroids and azathioprineComplete response

Teasley et al. [9]Female30Left eyeGraves’ diseaseDapsoneComplete response

Fournié et al. [10]Male78Left eyeMultiple myelomaCyclophosphamide, systemic corticosteroids, and human intravenous immunoglobulinsComplete response