Case Report
Mycosis Fungoides of the Oral Cavity: Fungating Tumor Successfully Treated with Electron Beam Radiation and Maintenance Bexarotene
Table 1
Differential diagnosis of oral tumors.
| Disease | Oral lesion description | Diagnostic clues |
| Malignancy/premalignancy | | | Squamous cell papilloma | Discrete exophytic papillary lesions (verruca): occur at any intraoral site | History of human immunodeficiency virus infection; association with cutaneous warts on fingers | Squamous cell carcinoma | Nonhealing ulcers, papules, or plaques: occur most frequently at the floor of the mouth and soft palate | History of tobacco and alcohol consumption; mechanical trauma from ill-fitting dentures |
| Mesenchymal neoplasms and tumor-like lesions | | | Fibrous and vascular overgrowths | Discrete lesions of cheek or tongue | History of chronic irritation, usually from some tooth-related cause or chronic cheek/tongue biting | Pyogenic granuloma | Exuberant overgrowths usually at the gingiva but can occur at any intraoral site | May bleed spontaneously or following irritation due to extreme vascularity |
| Odontogenic tumors and cysts | | | Ameloblastoma | Oral swellings occurring on the mandible that typically produce multicystic appearance on radiograph | Painless and slow growing; untreated, may reach substantial size | Odontogenic cysts | Oral swellings arising adjacent to teeth that usually produce a well-demarcated cyst on radiograph | Painless and slow growing |
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