Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage

Figure 5

20x magnification of tissue taken directly below the perforated cartilage (cartilage removed during immunostaining). Large pleomorphic cells staining positively for AE1/AE3 (arrow) are present in the posterior ear skin. The normal pilosebaceous units, eccrine ducts, and epidermis in the normal posterior ear skin serve as positive controls.