Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients

Table 2

The main histologic findings in 3 Jordanian patients with prurigo pigmentosa.

Lesion biopsied	Patient 1	Patient 2	Patient 3
	Papulovesicular neck lesion	Erythematous papule on the back	Erythematous urticated plaque on the neck
Epidermal changes
Orthokeratosis	+	+	+
Parakeratosis	−	−	−
Scale crust	−	+	−
Epidermal hyperplasia	+	+	+
Keratinocyte necrosis	+	+	+
Spongiosis	+	+	+
Vesiculation	−	−	−
Neutrophilic exocytosis	−	+	−
Basal cell vacuolization	+	+	+
Secondary impetiginization	−	−	−
Dermal changes
Perivascular lymphocyte infiltrate	+	+	+
Perivascular polymorphonuclear infiltrate	+	+	+
Papillary dermal oedema	+	+	+
Pigment incontinence	−	−	−