Case Report
Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients
Table 2
The main histologic findings in 3 Jordanian patients with prurigo pigmentosa.
| Lesion biopsied | Patient 1 | Patient 2 | Patient 3 | Papulovesicular neck lesion | Erythematous papule on the back | Erythematous urticated plaque on the neck |
| Epidermal changes | | | | Orthokeratosis | + | + | + | Parakeratosis | − | − | − | Scale crust | − | + | − | Epidermal hyperplasia | + | + | + | Keratinocyte necrosis | + | + | + | Spongiosis | + | + | + | Vesiculation | − | − | − | Neutrophilic exocytosis | − | + | − | Basal cell vacuolization | + | + | + | Secondary impetiginization | − | − | − |
| Dermal changes | | | | Perivascular lymphocyte infiltrate | + | + | + | Perivascular polymorphonuclear infiltrate | + | + | + | Papillary dermal oedema | + | + | + | Pigment incontinence | − | − | − |
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