A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography

Table 1

Patients, tumors, and treatment characteristics. Patients 1 and 3 required half a tube per application of the commercially available ingenol mebutate gel (Picato® Gel, 500MCG/G), while patients 2 and 4 applied the whole tube per application.

Patient/Tumor Number	Gender	Age	Co-morbidities	Concomitant medication	Tumor Localization	Maximal diameter (mm)
1	F	79	Pacemaker, arterial hypertension, diabetes mellitus, hypothyroidism	Aminosalycilic acid, propranol, amlodipine, ramipril, atorvastin, dapagliflozin, vildagliptin, glycazide, thiamazole	Nose	20
2	F	81	Asthma, atrial fibrilation	Flixotide, budesonide, formoterol, aminosalycilic acid, isoprenaline	Preauricular	70
3	F	68	Diabetes	Sitagliptin	Mandible	22
4	M	78	Atrial fibrilation, arterial hypertension,	Carvedilol, propafenone, rivaroxaban, olmesartan	Chest	33