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Case Reports in Dermatological Medicine
Volume 2019, Article ID 8309103, 5 pages
https://doi.org/10.1155/2019/8309103
Case Report

Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study

1GIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, India
2Global Institute of Stem Cell Therapy and Research, 4660 La Jolla Village Drive, San Diego, CA 92122, USA

Correspondence should be addressed to Anand Srivastava; moc.ratsoig@dnana

Received 6 April 2019; Accepted 21 April 2019; Published 2 May 2019

Academic Editor: Jacek Cezary Szepietowski

Copyright © 2019 Rajasekar Seetharaman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. In this report, we discuss our findings about a scalp psoriasis suffering patient with a Psoriasis Scalp Severity Index (PSSI) score of 28, who was treated with Mesenchymal stem cell conditioned media (MSC-CM). Remarkably, complete regression was recorded within a treatment period of one month only (PSSI score of 0). A number of bioactive factors like cytokines and growth factors secreted by MSCs in the conditioned medium are very likely to be the principle molecules which play a vital role in skin regeneration. Treatment using MSC-CM appears to be an effective tool for tackling the psoriatic problem and, thus, may offer a new avenue of therapy which could be considered as an alternative approach to overcome the limitations of the cell-based therapy.