IVIG and under Burn Unit Care Yield Favorable Outcomes in Pediatric Patients with Toxic Epidermal Necrolysis: A Case Report and Literature Review

Table 2

Literature review of 39 cases of TEN (treatment approaches and mortality rate).

Study	Number of patients	TEN : SJS	M : F	IVIG (n)	IVCS (n)	Another drug modality	TBSA% (mean ± SD)	BU/ICU (n)	Mortality (n)
Adzick et al. [12]	4	4 : 0	2 : 2	0	0	—	86.25 ± 10.23	4	1
Inamo et al. [13]	3	2 : 1	3 : 0	0	0	Ulinastatin	N/A	0	0
Zahra and Soror [14]	1	1 : 0	0 : 1	1	0	—	90%	1	0
Moudgil et al. [15]	2	0 : 2	1 : 1	2	0	—	N/A	0	0
Prais et al. [16]	4	N/A	0 : 4	4	4	—	N/A	0	0
Spies et al. [11]	15	15 : 0	9 : 6	0	0	—	76 ± 5	15	1
Stella et al. [17]	9	9 : 0	4 : 5	9	9	LMWH	61	9	1
Straussberg et al. [18]	1	0 : 1	0 : 1	1	1	—	N/A	0	0

TEN: toxic epidermal necrolysis, SJS: Stevens–Johnson syndrome, IVIG: intravenous immunoglobulin, IVCS: intravenous corticosteroid, TBSA: total body surface area affected, BU: burn unit, ICU: intensive care unit, LMWH: low molecular weight heparin, and N/A: not available.